Dr. Luigi Montano UroAndrologo ospedaliero

Curriculum in breve

UroAndrologo ospedaliero dell’ASL Salerno, esperto in Patologia Ambientale e Medicina dello Stile di Vita, dottorato in Biologia dell’Evoluzione ed Ecologia, Past President della Società Italiana di Riproduzione Umana (SIRU) (2017 -2023).
Ha conseguito l'abilitazione Scientifica Nazionale a Prof. Ordinario in Urologia (giugno 2026).
Ha ideato e coordina il progetto di Ricerca EcoFoodFertility, (www.ecofoodfertility.it), uno studio integrato e interdisciplinare di biomonitoraggio umano in corso nelle aree a rischio ambientale non solo d'Italia, che utilizza approcci omici su diverse matrici biologiche, in particolare, sul seme umano, “Sentinella della Salute Ambientale e Generale”.
Il Progetto introduce un nuovo modello per la valutazione precoce dell'impatto ambientale sulla salute umana, per la prevenzione primaria e la resilienza delle popolazioni nelle aree a rischio.
E’ stato il primo autore al mondo a pubblicare la presenza di microplastiche nell’apparato urinario e riproduttivo maschile e femminile e ad introdurre sul fronte della resilienza umana un nuovo paradigma della Dieta Mediterranea basata sul alimenti Biologici (coniando la MEDEUBIOTICA) come strumento di tutela della salute riproduttiva e del benessere complessivo, capace di controbilanciare gli inquinanti ambientali ed i loro effetti e costituendo un vero e proprio scudo biologico per ridurre il carico di patologie riproduttive e cronico-degenerative nelle generazioni attuali e future. Tale approccio innovativo può rappresentare un punto di riferimento per operatori sanitari, ricercatori, cittadini e per l’intero settore agroalimentare.
Ha all'attivo numerose pubblicazioni su riviste internazionali, diversi capitoli di libri su salute ambientale e riproduttiva, ricevuto diversi premi nazionali ed internazionali, fra cui in ben tre edizioni (2021,2024,2026) il riconoscimento di Paladino Italiano della Salute ed il premio UNESCO (2024).
Relatore a numerosi congressi nazionali ed internazionali, attualmente coordina diversi progetti di ricerca.

Elenco pubblicazioni scientifiche su google

Profilo ResearchGate

Scopus

Web of Science Researcher IDW-2067-201

Attività scientifica

• 1. EcoFoodFertility – Environmental and food impact assessment on male reproductive function. L.Montano, L. Iannuzzi, J. Rubes, C. Avolio, C. Pistos, A. Gatti, S. Raimondo, T.Notari, Andrology 2(Suppl.2):69, 2014
• 2. Valutazione dell’impatto ambientale sull’integrità del DNA nemaspermico mediante misurazione della proteina p53: dati preliminari (Progetto EcoFoodFertility).L. Montano, S. Raimondo, T. Notari, P. Bergamo, M. Rossi, D.Luongo, MG. Volpe, L. Iannuzzi Arch.Ital.Urol.Androl. 87 (Suppl.1):2, 2015
• 3. Evaluation of Enviornmental Impact on Sperm DNA integrity by Sperm Chromatin Dispersion Test ad p53 Elisa: Preliminary data. (EcoFoodFertility Project). L. Montano, T. Notari, S. Raimondo, P. Bergamo, M. Rossi, D. Luongo, MG Volpe, L. Iannuzzi. Reproductive Toxicology. Vol. 56: 20, 2015
• 4. Il liquido seminale: Marker precoce e sensibile di esposizione ambientale. Biomonitoraggio di elementi in traccia nel sangue e nel seme e relazione con la qualità seminale e lo stato RedOx (Progetto di Ricerca EcoFoodFertility). L.Montano, P. Bergamo, MG Volpe, S. Lorenzetti, A.Mantovani, T.Notari, E. Cocca, S. Cerullo,P. Cerino, M.Di Stasio. (Arch. Ital . Urol. Androl. Vol.88 (Suppl.1): 2, 2016
• 5. Environmental impact assessment on human fertility in males living in polluted areas of Campania Region by cytokinesis-block micronucleus assay and SCE test. V. Genualdo, A. Perucatti, A. Iannuzzi, C. Iorio, S.Ianuario, D. Incarnato, C.Rossetti, L.Montano, L. Iannuzzi. Clinical Cytogenetics, Mutagenesis. p.20, 50, 2016
• 6. Human semen as an early, sensitive biomarker of environmental exposure of healthy men living in highly polluted areas: a pilot biomonitoring study of trace elements in blood and semen and relationship with sperm quality and RedOx status. Paolo Bergamo, Maria Grazia Volpe, Stefano Lorenzetti, Alberto Mantovani Tiziana Notari, Ennio Cocca, Stefano Cerullo, Michele Di Stasio, Pellegrino Cerino and Luigi Montano*. Reproductive Toxicology.2016. 66:1-9.
• 7. Environmental pollutants: genetic damage and epigenetic changes in male germ cells. C.Vecoli, L.Montano, MG Andreassi. 2016. Environ Sci Pollut Res Int. 23(23):23339-48. doi 10.1007/s11356-016-7728-4
• 8. Effects of highly polluted environment on sperm telomere length: a pilot study. Cecilia Vecoli, Luigi Montano, Andrea Borghini, Tiziana Notari,Antonino Guglielmino, Antonella Mercuri, Stefano Turchi, Maria Grazia Andreassi. Int. J. Mol. Sci. 2017, 18, 1703; doi:10.3390/ijms18081703
• 9. Innovative environmental scanning electron microscopy observations of the human semen in the study of male infertility (preliminary data). Antonietta Gatti, Luigi Montano. Reproductive Toxicology Vol. 72:38, 2017 doi.org/10.1016/j.reprotox.2017.06.154
• 10. The role of human semen for assessing environmental impact on human health in risk areas: Novels and early biomarkers of environmental pollution. EcoFoodFertility project.Luigi Montano,Paolo Bergamo,Maria Grazia Andreassi,Cecilia Vecoli,Maria Grazia Volpe,Stefano Lorenzetti, Alberto Mantovani, Tiziana Notari. Reproductive Toxicology Vol. 72: 44-45. 2017 doi.org/10.1016/j.reprotox.2017.06.169
• 11. The role of the Mediterranean diet on sperm morphology in healthy men living in polluted area (EcoFoodFertility project).Luigi Montano, Giuseppe Porciello, Anna Crispo, Stefano Lorenzetti, Salvatore Raimondo, Stefania Ubaldi, Michela Caputo. Reproductive Toxicology Vol. 72: 45. 2017 doi.org/10.1016/j.reprotox.2017.06.170
• 12. Duplication of Yq- and proximal Yp-arms with deletion of almost all PAR1 (including SHOX) in a young man with non-obstructive azoospermia, short stature and skeletal defects. Dino Cancemi, Alessandra Iannuzzi, Angela Perucatti, Luigi Montano, Oronzo Capozzi, Carmine Spampanato, Maria Luisa Ventruto, Maria Urciuoli, Leopoldo Iannuzzi, Valerio Ventruto. Appl Genetics oct. 2017 DOI 10.1007/s13353-017-0412-7
• 13. Duplication of Yq- and proximal Yp-arms with deletion of almost all PAR1 (including SHOX) in a young man with non-obstructive azoospermia, short stature and skeletal defects. Dino Cancemi, Alessandra Iannuzzi, Angela Perucatti, Luigi Montano, Oronzo Capozzi, Carmine Spampanato, Maria Luisa Ventruto, Maria Urciuoli, Leopoldo Iannuzzi, Valerio Ventruto. Appl Genetics oct. 2017 DOI 10.1007/s13353-017-0412-7
• 14) EcoFoodFertility Project – from the crisis to the model –A new model for environmental impact assessment and for primary prevention in risk areas. Luigi Montano. 2017 Lambert Accademic publishing.
• 15) Rapid evaluation of free fatty acids concentration in edible hemp food chain using ATR-FTIR spectroscopy – Siano, F., Sorrentino, G., Paolucci, M., Montano, L., Volpe, M.G. 3rd Imekofoods October 1st- 4th 2017. Thessaloniky (Greece)
• 16) Human sperm cells sentinel of our living environment. Luigi Montano and Alberto Mantovani.Openaccessgovernment. Nov 2017. https://www.openaccessgovernment.org/human-sperm-cells-sentinel-of-our-living-environment/38889/
• 17) Sperm DNA fragmentation: an early and reliable marker of air pollution. Liana Bosco, Tiziana Notari, Giovanni Ruvolo, Maria C. Roccheri, Chiara Martino, Rosanna Chiappetta, Domenico Carone, Giosuè Lo Bosce, Laura Carrillo, Salvatore Raimondo, Antonino Guglielmino, Luigi Montano*.Environ Toxicol Pharmacol. 2018 Mar;58:243-249. doi: 10.1016/j.etap.2018.02.001 Epub 2018 Feb 7 .
• 18) The role of human semen as an early and reliable tool of environmental impact assessment on human health. Luigi Montano, Paolo Bergamo, Maria Grazia Andreassi, Stefano Lorenzetti. Full Chapter in Final Book Title & ISBN: Spermatozoa - Facts and Perspectives, " 978-1-78923-171-7. InTechOpen June 13th 2018 http://dx.doi.org/10.5772/intechopen.73231
• 19) ATR- FTIR spectroscopy application as a tool toderive biochemical signature differences inblood and human semen due to pollution.(Preliminary data). EcoFoodFertility Project. Luigi Montano, Maria Grazia Volpe, ,Costantina Barbarisi, Valentina De Vito. Reproductive Toxicology septemebre 2018 Volume 80, page 28. https://doi.org/10.1016/j.reprotox.2018.06.058
• 20) Potential role of p53 protein as a novel biomarker of sperm quality, able to predict the success of ART techniques. EcoFoodFertility Project. Luigi Montano, Salvatore Raimondo, Maria Cira Gentile, Tiziana Notari, Liana Bosco, Tommaso Gentile. Reproductive Toxicology Volume 80, September 2018 page 29. https://doi.org/10.1016/j.reprotox.2018.06.059
• 21) The role of synergic action between alpha-Tocoferol and lifestyle on reduction of p53 protein in human spermatozoa. (Preliminary data. EcoFoodFertility Project. Luigi Montano, Salvatore Raimondo, Maria Cira Gentile,Tiziana Notari Rosa Bifulco, Giuseppe Porciello, Tommaso Gentile. Reproductive Toxicology Volume 80, September 2018, Pages 29-30 https://doi.org/10.1016/j.reprotox.2018.06.060
• 22) Il Seme Sentinella – Un’antenna Epidemiologica nelle aree a rischio ambientali d’Italia a tutela della salute pubblica delle attuali e future generazioni. Luigi Montano. Io Uomo- Rivista quadrimestrale della Società Italiana di Andrologia, Novembre 2018, Pag. 12-13
• 23) Terra dei Fuochi, the starting point. The role of prevention and complementary medicine in the clinical practice. A. Del Buono, A. D’Orta, G, Tarro, P. Rossi, S. Papa, L.Iodice, A.Abbadessa, L. Montano, G. Portale, M. Beretta, R. Di Francia. World Cancer Global Journal, 2018; 5 (3) e 112, Pag. 1-7
• 24) Impatto sulla salute degli inquinanti indoor. Luigi Montano.Capitolo In “Inquinamento Indoor” a cura della Fondazione Veronesi. UTET Dicembre 2018
• 25) p53 protein evaluation on spermatozoa DNA in fertile and infertile males. Salvatore Raimondo, Tommaso Gentile, Mariacira Gentile, Alessia Morelli, Francesca Donnarumma, Felice Cuomo, Stefania De Filippo, Luigi Montano. J. Human Reproductive Science. Volume 12, June 2019, pages 114-121 DOI: 10.4103/jhrs.JHRS_170_18
• 26) Third party Reproduction: The Italian Society of Human Reproduction (SIRU) Consensus Meeting: p.782. A Guglielmino, P Viganò, L Montano, A Allegra, A Liprino, F Giacone, S Palini, A Paffoni, M Baldi, Z Donarelli, F Tomei, D Carone, E Papaleo, P Inaudi, E Somigliana. Human Reproduction 2019.
• 27) Human semen: Excellent bioaccumulator of volatile Organic compounds (VOCs). (EcoFoodFertility project). L. Montano, V. Longo, A. Forleo, S. Pappalardo, A. Ferramosca, P. Siciliano, S. Capone. European Urology Supplements, Volume 18, Issue 9, e3334 October 2019Volume 18, Issue 9, Page e3334 DOI: https://doi.org/10.1016/S1569-9056(19)33779-0
• 28) Sperm p53 concentration: A potential new biomarker for environmental pollution. Preliminary data. (EcoFoodFertility project). L. Montano, S. Raimondo, T. Notari, M. Gentile, L. Bosco, T. Gentile. European Urology Supplements, Volume 18, Issue 9, e3335. October 2019. DOI: https://doi.org/10.1016/S1569-9056(19)33780-7
• 29) Lifestyle, environmental exposures and male fertility in healthy young men in North Italy. C Zani, D Zani, F Donato, M Marullo, G C V Viola, S Lorenzetti, L Montano. European Journal of Public Health, Volume 29, Issue Supplement_4, November 2019, ckz186.459, https://doi.org/10.1093/eurpub/ckz186.459
• 30) Double Approach to Study VOC Composition in Biofluids of Young Men Living in the “Land of Fires” in Campania Region. V. Longo, A. Forleo, A. Ferramosca, P.Siciliano, S.Capone, S. Pappalardo, L. Montano. February 2020. Lecture Notes in Electrical Engineering 629:103-109 DOI: 10.1007/978-3-030-37558-4_16
• 31) Protective effect of curcumin towards cadmium and polycyclic aromatic hydrocarbons toxicities: The EcoNutraPrevention Project. I. Tedesco, M.Russo, S.Moccia, C. Cervellera, C.Spagnuolo, V. Carbone, P. Minasi, L.Montano, P. Verze, M. Capece, V. Mirone, A. Baraschino, M. De Rosa, M.G. Volpe, G.L. Russo. Nutrition, Metabolism & Cardiovascular Diseases, March 2020, Volume 30, Issue 3, pag. 240 DOI: https://doi.org/10.1016/j.numecd.2019.12.036
• 32) Discovery of the Involvement in DNA Oxidative Damage of Human Sperm Nuclear Basic Proteins of Healthy Young Men Living in Polluted Areas. G. Lettieri, G. D'Agostino, E. Mele, C. Cardito, R. Esposito, A. Cimmino, A. Giarra, M. Trifuoggi, S. Raimondo, T. Notari, F. Febbraio*, L. Montano*, M. Piscopo*. Int J Mol Sci . 2020 Jun 12;21(12):E4198. doi: 10.3390/ijms21124198
• 33) Semen Quality as a Potential Susceptibility Indicator to SARS-CoV-2 Insults in Polluted Areas. L. Montano*, IM. Bonapace, F. Donato, PM. Bianco, A. Guglielmino , M.Piscopo. Preprint doi: 10.20944/preprints202006.0314.v1
• 34) Probable role of KLK3 in menstrual cycle of young women. Mariacira Gentile, Francesca Donnarumma, Giusy Esposito, Tommaso Gentile, Ida Ferrara, Claudia Crescenzo, Mariangela Palmieri, Salvatore Raimondo & Luigi Montano. Endocrine Abstracts (2020) 70 EP388 | doi: 10.1530/endoabs.70.EP388
• 35) Environmental pollution affects the protamine-histone content in human sperm and changes their properties making able to promote DNA oxidative damage: the contribution of molecular investigations.M Piscopo, G Lettieri, F Febbraio, G D'Agostino, E Mele, C Cardito, L.Montano. Human Reproduction 35, 75-75 (2020)
36) Reproductive biomarkers as early indicators for assessing environmental health risk. L.Montano, in Marfe,G., and Di Stefano C. Toxic Waste Management and Health Risk, BenthamScience Publishers eBook eISBN 978-981-14-5474-5 (2020) Doi: 10.2174/97898114547451200101 https.//www.eurekaselect.com/185279/chapter
• 37) Molecular Alterations in Spermatozoa of a Family Case Living in the Land of Fires—A First Look at Possible Transgenerational Effects of Pollutants. Gennaro Lettieri, Federica Marra, Claudia Moriello, Marina Prisco, Tiziana Notari, Marco Trifuoggi, Antonella Giarra, Liana Bosco, Luigi Montano*, Marina Piscopo*. Int. J. Mol. Sci. 2020, Volume 21, Issue 18, 6710.
• 38) Reproductive biomarkers as early indicators for assessing environmentalhealth risk. L.Montano, in Marfe,G., and Di Stefano C. Toxic Waste Management and Health Risk, BenthamScience Publishers eBook eISBN 978-981-14-5474-5 (2020) Doi: 10.2174/97898114547451200101 https.//www.eurekaselect.com/185279/chapter
• 39) Molecular Alterations in Spermatozoa of a Family Case Living in the Land of Fires—A First Look at Possible Transgenerational Effects of Pollutants. Gennaro Lettieri, Federica Marra, Claudia Moriello, Marina Prisco, Tiziana Notari, Marco Trifuoggi, Antonella Giarra, Liana Bosco, Luigi Montano*, Marina Piscopo*. Int. J. Mol. Sci. 2020, Volume 21, Issue 18, 6710.
• 40) Interdisciplinary Collaboration between Environmental Health and Clinical Experts on Cancers and Infertility Associated with Exposure to Endocrine Disruptors (2020).A. Fucic, A. Mantovani and L. Montano. https://pubs.rsc.org/en/content/ebook/978-1-78801-741-1 - https://doi.org/10.1039/9781839160738-00483
• 41) Effects of a lifestyle change intervention on semen quality in healthy young men living in highly polluted areas in Italy: the FASt randomized controlled trial. (2021). Montano L*, Ceretti E, Donato F, Bergamo P, Zani C, Viola GCV, Notari T, Pappalardo S, Zani D, Ubaldi S, Bollati V, Consales C, Leter G, Trifuoggi M, Amoresano A, Lorenzetti S.EurUrol Focus 2021 Feb 10;S2405-4569(21)00041-9. doi: 10.1016/j.euf.2021.01.017.
• 42) SARS-CoV-2 Detection in Fecal Sample from a Patient with Typical Findings of COVID-19 Pneumonia on CT but Negative to Multiple SARS-CoV-2 RT-PCR Tests on Oropharyngeal and Nasopharyngeal Swab Samples. Brogna B, Brogna C, Petrillo M, Conte AM, Benincasa G, Montano LandPiscopoM.Medicina 2021, 57(3), 290; https://doi.org/10.3390/medicina57030290
• 43) Microplastics in the Aquatic Environment: Occurrence, Persistence, Analysis, and Human Exposure. Ricciardi M,PirontiC, Motta O, Miele Y, Proto A andMontano L. Water 2021, 13(7), 973; https://doi.org/10.3390/w13070973
• 44) KLK3 as a possible novel early biomarker of environmental exposure in young women living in Polluted area (EcoFoodFertility project). Raimondo S, Gentile M,. EspositoG, Gentile T, Ferrara I, Crescenzo C, Palmieri M, Cuomo F, De Filippo S, Piscopo M, Montano L*.Preprint on Research Square April 2021 DOI: https://doi.org/10.21203/rs.3.rs-356029/v1
• 45) Semen analysis in “urology-naïve” patients: a chance of uroandrological screening in young male. Toso S, Ticonosco M, Rabito S, Sighinolfi MC, Ferrar Ri, Rochira V, Santi D, Trenti T, Montano L, Rocco B, Micali S. Preprint on ResearchSquare, April 2021 DOI: 10.21203/rs.3.rs-405974/v1
• 46) Endocrine-Disrupting Compounds: An Overview on Their Occurrence in the Aquatic Environment and Human Exposure. Pironti C, Ricciardi M, Proto A, Bianco PM,Montano L*,andMottaO*Water 2021, 13(10), 1347; https://doi.org/10.3390/w13101347
• 47) Blood, urine and semen Volatile Organic Compound (VOC) pattern analysis for assessing health environmental impact in highly polluted areas. Longo V,ForleoFerramosca A, Notari T, Pappalardo S, Siciliano P, Capone S, Montano L.Environmental Pollution, Available online 24 May 2021, 117410https://doi.org/10.1016/j.envpol.2021.117410
• 48) Semen quality as a potential susceptibility indicator to SARS-CoV-2 insults in polluted areasMontano L*., Donato F, Bianco PM, Lettieri G, Guglielmino A, Motta O, Bonapace IM*,Piscopo M*. Journal. Environmental Science and Pollution Research, may 2021 (), 1-10 DOI 10.1007/s11356-021-14579-x
• 49) Air pollution and COVID-19: a possible dangerous synergy for male fertility. Montano L*, Donato F, Bianco PM, Lettieri G, Guglielmino A, Motta O, Bonapace IM,* Marina Piscopo M*.Int. J. Environ. Res. Public Health 2021, 18, x. https://doi.org/10.3390/xxxxx
• 50) Chromatin Maturity Index (CMI) in unfixed and live spermatozoa and Aniline Blue (AB) stained as an additional evaluation parameter in idiopathic male infertility. Notari T, Piscopo M, Bosco L, Pecoraro S, Serra N, Ricciardi D, Capra G, Montano L.Human Reproduction, Volume 36, Issue Supplement_1, July 2021, deab130.073, https://doi.org/10.1093/humrep/deab130.073Published: 06 August 2021
• 51) Could Kallikrein-Related Serine Peptidase 3 Be an Early Biomarker of Environmental Exposure in Young Women? Raimondo S, Gentile M, Esposito G, Gentile T, Ferrara I, Crescenzo C, Palmieri M, Cuomo F, De Filippo S, Lettieri G, Piscopo M,* andMontano L 5,6*.Int. J. Environ. Res. Public Health 2021, 18, 8833. https://doi.org/10.3390/ ijerph18168833
• 52) Presence of p53 Protein on Spermatozoa DNA: A Novel Environmental Bio-Marker and Implications for Male Fertility. August 2021 DOI: 10.5772/intechopen.99559 In book: P53 - A Guardian of the Genome and Beyond LicenseCC BY 3.0. Salvatore Raimondo, MariaciraGentile,Tommaso Gentile and Luigi Montano
• 53)Microplastics in the Environment: Intake through the Food Web, Human Exposure and Toxicological Effects. Concetta Pironti, Maria Ricciardi,Oriana Motta*, Ylenia Miele, Antonio Proto and Luigi Montano*. Toxics 2021, 9(9), 224; https://doi.org/10.3390/toxics9090224